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Chemistry for Sustainable Development

2009 year, number 2

Some Prenylated Phenols of Rhododendron adamsii: Isolation, Modification and Pharmacological Tests

A. D. Rogachev, N. I. Komarova, D. V. Korchagina, M. P. Dolgikh, I. V. Sorokina, D. S. Baev, T. G. Tolstikova, V. V. Fomenko, N. F. Salakhutdinov
Keywords: Rhododendron adamsii, meroterpenoids, xanthenols, coagulants
Pages: 191-198


Methyl ester of cannabigerorcynic acid 1, previously unknown derivative of octahydroxanthenol 2 and daurichromenic acid 4 were isolated from the lipophilic extracts of Rh. adamsii. Derivatives of compounds 1 and 2 were obtained. It was shown that xanthenol 2 possesses coagulating and hypothermic effect. Methyl ester of cannabigerorcynic acid was discovered in a natural object for the first time.