Effect of the Components of Biological Environment on the Formation of Hydroxyapatite
O. A. GOLOVANOVA1,2, E. YU. PONAMOREVA1 and O. V. FRANK-KAMENETSKAYA2
1Dostoevsky Omsk State University, Omsk (Russia)
2Saint Petersburg State University, Saint Petersburg (Russia)
Keywords: synthesis, hydroxyapatite, crystallization, electrokinetic properties, x potential, additives, adsorption, Langmuir and Freundlich models
Pages: 251-256
Abstract
Using the modified procedure of the synthesis of non-stoichiometric hydroxyapatite species at the physiological pH and solution temperature, we obtained the solid phases with the Ca/P atomic ratios within the range from 1.58±0.01 to 1.67±0.01. According to the data of X-ray phase an alysis, these samples are composed of hydroxyapatite. The effect of inorganic additives (phosphate, oxalate, carbon ate anions, magnesium cations) and organic ones (amino acids) on the crystallization of hydroxyapatite was studied.
The
electrokinetic properties of the sol of synthesized hydroxyapatites of
different stoichiometric composition were studied. It was established that the
charge and the value of î potential of hydroxyapatite particles depend on the
Ca/P atomic ratio. It was discovered that the character of amino acid
interaction with non-stoichiometric hydroxyapatite differs from that with the
stoichiometric one. It was shown that adsorption observed on the samples of
synthesized hydroxyapatite is described within Langmuir and Freundlich models. |
