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Chemistry for Sustainable Development

2005 year, number 1

A Substance with Cytostatic and Apoptosis-Inducing Activity from Burdock Roots

Institute of Petroleum Chemistry, Siberian Branch of the Russian Academy of Sciences,
Prospekt Akademicheskiy 3, Tomsk 634021 (Russia) E-mail:
Pages: 119-122


For the first time, β-asparagine was isolated from burdock roots and identified. It was established that β-asparagine extracted from roots exhibits cytostatic and apoptosis-inducing activity. Synthetic L-asparagine (manufactured in Japan) exhibits neither cytostatic nor apoptosis-inducing activity.