Home – Home – Jornals – The journal "Ateroskleroz" 2011 number 2

In this article up-to-date notions of the variants of atherosclerotic plaque evolution are reviewed, atherogenesis is described as chronic inflammatory and fibrotic process, the major cytokines and mediators involved in the process are characterized. The paper lays special emphasis on the role of interrelationships between mononuclear phagocytes and the extracellular matrix-producing cells.