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Chemistry for Sustainable Development

2003 year, number 2

Comparative Analysis of Biogenous Carbonate Hydroxylapatite and of Its Synthetic Analog as a Material for Osteoplastics

NADEZHDA A. PALCHIK1, ALEXANDER M. GONCHAR2, TAMARA N. GRIGORYEVA1, VALENTINA N. STOLPOVSKAYA1, TATIANA N. MOROZ1 and LEONID V. MIROSHNICHENKO1
1United Institute of Geology, Geophysics and Mineralogy,
Siberian Branch of the Russian Academy of Sciences, Pr. Akademika Koptyuga 3,
Novosibirsk 630090 (Russia), E-mail: nadezhda@uiggm.nsc.ru
2Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences,
Pr. Akademika Koptyuga 4, Novosibirsk 630090 (Russia)
Pages: 389-394

Abstract

A comparative analysis of biogenous and synthetic carbonate hydroxylapatite of various degree of crystallinity has been carried out. The analysis of chemical composition of enamel and dentine was carried out on an X-ray microanalyzer, that of the synthetic product on an X-ray fluorescence spectrometer. Crystallochemical characteristics were studied by X-ray diffractometry and molecular spectroscopy. Identity of structural characteristics and of the chemical composition of the specimens studied was demonstrated. Toxicological, mutagenic properties and histocompatibility of the synthetic apatite were studied. The material obtained was used for treatment of patients with defects of bone tissue.