Home – Home – Jornals – Chemistry for Sustainable Development 2016 number 6

A series of water soluble, nontoxic, available in the production of salts and ion liquids that are protatranes and their analogs of the formula ArХCH₂COO^{- .}НN⁺R₁R₂CH₂CH₂OH, where Ar = aryl, indolyl; X = O, S, SO₂, Se; R₁, R₂ = H, Me, CH₂CH₂OH, etc. were synthesized by the reaction of biogenic hydroxyethyl amines with biologically active arylchalcogenylacetic acids. Earlier, their high and diverse pharmacological activities (immunotropic, antitumor, antimetastatic, antithrombotic, adaptogenic, etc .) were detected. Additionally, protatranes in low (nano) concentrations (to 1 ∙ 10^-10 mass %) turned out to be powerful biostimulators of various biological processes. This review discusses the study results of the stimulatory action of protatranes on animals, plants, fungi, bacteria, cells, enzymes. It was shown that the application of protatranes in agriculture enhanced the productivity of plant cultivation, sericulture, aviculture, animal husbandry, fish breeding, as well as the production of fertilizers from wastes (lignin). The use of protatranes in biotechnology contributes to an increase in the rate and the selectivity of processes, as well to the production yield, is important for creating new economic methods of the preparation of malt, bakery yeast, fodder and dietary protein, citric acid, bioethanol, lactic Bifidumbacterin, ginseng biomass, stem cells, etc . Stimulators were found for microbiology, and nutrient media for the growth of staphylococcal and other bacteria that allow repeatedly speeding up the analysis and diagnostics of socially significant diseases and, consequently, timely prescribing adequate treatment were elaborated.