Synthesis and Properties of Metal Chelates Based on Natural Оі-Pyrone - Maltol
S. A. Mukha, I. A. Antipova, S. A. Medvedeva, V. V. Saraev, L. I. Larina, A. V. Tsyrenzhapov, B. G. Sukhov
Pages: 457-466
Abstract
Chelate compounds of maltol, extracted from the needles of Siberian abies, with the ions of such metals as copper (II), cobalt (II), nickel (II), zinc (II), iron (III), aluminium (III), chromium (III) were synthesized. The features of complexation were revealed and the corresponding conditions were optimised. The composition and structure of metal complexes were confirmed with the help of physicochemical and spectral methods UV, IR, NMR), structural characteristics were obtained with the help of EPR. Stability constants were determined; the complexes were arranged into the stability row under the conditions of physiological pH of the medium. The biological activity of ferric and copper maltolates as potential preparations to cure blood diseases was demonstrated.
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