Application of mechanochemistry-assisted treatment to aqueous extraction of isofraxidin from Acanthopanax senticosus
Y. Liu, Y. P. Xu and L. J. Jin
Department of Bioscience and Biotechnology, School of Environmental & Biological Science & Technology, Dalian University of Technology, Dalian 116023 (China)
E-mail: liuying6416@sina.com
Pages: 189-195
Abstract
Mechanochemistry-assisted treatment (MT) was applied for the first time to extract isofraxidin from Acanthopanax senticosus using water as solvent. Six extraction variables, i.e. solvent, Na2CO3 content, sample granularity, extraction time, liquid/solid ratio (ml/g), extraction temperature were investigated with respect to the yield of isofraxidin. The most favourable conditions were obtained by using superfine powered plant material (D95 of 47 mm) with Na2CO3 content of 0.5 mass %, extracted with water (liquid/solid ratio of 20:1, ml/g) for 3 min at 25 oC. The results obtained using the optimized conditions were compared to those with heat reflux extraction. MT extraction was found to increase the yield of isofraxidin considerably while excluding organic solvents and reducing both extraction time and temperature.
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