Analysis of the Use of One-Dimensional Network Models of Blood Flow to Assess the Hemodynamic Coefficients in Stenosis Coronary Arteries
S. S. Simakov1,2,3
1Marchuk Institute of Computational Mathematics, Russian Academy of Sciences, Moscow, Russia
2Moscow Institute of Physics and Technology, Dolgoprudny, Russia
3Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Keywords: hyperbolic equations, conservation laws, coronary blood flow, hemodynamic indices, fractional blood flow reserve
Abstract
This paper presents an analysis of the effectiveness of using one-dimensional network models for virtual assessment of hemodynamic indices whose values are widely used in clinical practice to choose a treatment strategy for coronary heart disease with stenotic lesions of the coronary arteries. It is shown that existing approaches make it is possible to assess hemodynamic indices based on clinical data collected without intervention in the body with an accuracy comparable to the accuracy of the input data and direct measurements. It is also important to take into account the state of the myocardium microvasculature and its influence on the interpretation of modeling results and direct measurements in the clinic
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