Synthesis of 1-Alkylsulphonyl-4-X-2,3,5,6-tetrafluorobenzenes from Sulphanyl Derivatives
B. V. KOSHCHEEV, A. M. MAKSIMOV
Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
Keywords: polyfluoroaromatic compounds, sulphones, sulphanes, hydrogen peroxide
Pages: 619–623
Abstract
The interaction of alkyl(4-X-2,3,5,6-tetrafluorophenyl)sulphanes (X = H, CF3) containing difluoromethyl and benzyl groups as alkyl components with hydrogen peroxide in acetic or trifluoroacetic acid gave the corresponding sulphonyl derivatives. The effect of the acid used on the reaction result was established in the case of (difluoromethyl)[4-(trifluoromethyl)-2,3,5,6-tetrafluorophenyl]sulphane. The synthesis of 1-alkylsulphonyl-2,3,5,6-tetrafluorobenzenes scaling possibility to tens of grams was demonstrated. Product yields were 84-97%.
DOI: 10.15372/CSD2023509
EDN: YAZCKO
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