ATHEROCALCINOSIS OF THE ARTERIAL WALL AND ITS ASSOCIATION WITH DISORDER OF BLOOD LIPOPROTEIN PROFILE, MINERAL EXCHANGE AND STRUCTURAL CHANGES OF ACHILLES TENDON (ACCORDING TO COMPUTER TOMOGRAPHY DATA)
A.V. Anikina1,2, Yu.P. Nikitin1,2, M.E. Amelin3
1Research Institute of Internal and Preventive Medicine, 630089, Novosibirsk, Boris Bogatkov str., 175/1
2Institute of Cytology and Genetics of SB RAS, Novosibirsk, Russia
3Federal Center of Neurosurgery of Minzdrav of Russia, 630108, Novosibirsk, Nemirovich-Danchenko, 130/1
Keywords: атеросклероз, гиперхолестеринемия, сухожилие трехглавой мышцы голени, atherosclerosis, hypercholesterolemia, tendon of leg triceps muscle
Abstract
The purpose of the study was to study the possible association of hyperlipidemia, atherosclerosis and calcification of the arterial wall with the structural features of Achilles tendons. Material and methods. The group of examined patients was 148 people hospitalized in the vascular department of the Federal Center for Neurosurgery with the aim of stenting the internal carotid artery. All patients underwent a complete physical, instrumental examination and a biochemical blood test. Results. It was found that in individuals with a total cholesterol level higher than 5.0 mmol / L, the tendon cross-sectional area was larger than in subjects with cholesterol level less than 5.0 mmol / L ( p = 0.05), in patients with increased low density cholesterol (LDL-C) content the of the tendon cross-sectional area was 1.5 times larger in people with low LDL-C concentration. Further, all patients were divided into 2 groups depending on atherosclerotic plaque density. In patients with a low or medium atherosclerotic plaque density, the average tendon cross-sectional area was 335 mm2, the tendon density was 59HU, calcium deposition in the Achilles tendon was detected in 38 % cases, in the group with atherosclerotic plaque density - 441 mm2, 66 HU, 52 %, respectively. Conclusions. In individuals with high levels of fractions of atherogenic cholesterol, an increase in the cross-sectional area of the Achilles tendon is noted. There is also a tendency towards an increase in the incidence of calcinosis of the achilles tendons in patients with atherocalcinosis.
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