ASSOCIATION OF CHOLESTEROL ESTER TRANSFER PROTEIN GENE POLYMORPHISM AND DIET TO CHANGES IN SERUM LIPID PROFILE
N.V. Ozhiganova1,2, S.V. Mustafina2, E.V. Shakhtshneider1,2
1Federal Research Center Institute of Cytology and Genetics of SB RAS, 630090, Novosibirsk, Academician Lavrentev ave., 10
2Research Institute of Internal and Preventive Medicine - Branch of Federal Research Center Institute of Cytology and Genetics of SB RAS, 630089, Novosibirsk, Boris Bogatkov str., 175/1
Keywords: белок, переносящий эфиры холестерина, CETP, липидный профиль, липопротеины высокой плотности, средиземноморская диета, cholesterol ester transfer protein, CETP, lipid profile, high density lipoproteins, Mediterranean diet
Abstract
The cholesterol ester transfer protein regulates cholesterol efflux from peripheral tissues. The cholesterol ester transfer protein is encoded by CETP gene. The review describes the association of CETP gene variants with metabolic changes in different diets. The association of diet and metabolic changes depends on the sample size, individual and age characteristics of the patients, the duration of the observation, and the analysis of the spectrum of the CETP gene variants.
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