BIOCHEMICAL MARKERS OF ATHEROSCLEROTIC PLAQUE CALCIFICATION
N.A. Maslatsov, Yu.I. Ragino
Research Institute of Internal and Preventive Medicine - Branch of Federal Research Center Institute of Cytology and Genetics of SB RAS, 630089, Novosibirsk, Boris Bogatkov str., 175/1
Keywords: arterial calcification, atherosclerotic plaque, potential biomarkers, osteoprotegerin, osteopontin, osteonectin, osteocalcin
Abstract
The literature review highlights the results of foreign and Russian studies of recent years, devoted to the study of biochemical factors and potential biomarkers of calcification of the vascular wall, as well as atherosclerotic plaques of the coronary and carotid arteries. The results of the studies allow to clarify and to supplement the known mechanisms of calcification of the vascular wall. To date, the four most studied biomarkers of vascular calcification are most studied - osteoprotegerin, osteopontin, osteonectin and osteocalcin.
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