RELATIONSHIP BETWEEN THE STRUCTURE AND PHYSICOCHEMICAL CHARACTERISTICS OF 1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES
N. A. Nekrasova, S. V. Kurbatova
Korolev Samara National Research University, Samara, Russia
Keywords: 1,2,3,4-тетрагидрохинолин, высокоэффективная жидкостная хроматография, индексы связанности (индексы Рандича), факторы удерживания, 1,2,3,4-tetrahydroquinoline, high performance liquid chromatography, connectivity indices (Randic indices), retention factors
Abstract
A number of physicochemical characteristics of ten 1,2,3,4-tetrahydroquinoline derivatives synthesized for the first time, along with their third order Wiener and Randič indices are calculated by quantum chemical methods. Correlations between the topological indices, physicochemical parameters, and retention factors of the mentioned compounds are obtained for conditions of reversed-phase high performance liquid chromatography on porous graphitized carbon.
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