EFFECT OF THE TOPOLOGY OF BENZOTRIAZOLE DERIVATIVES ON THEIR CHROMATOGRAPHIC RETENTION UNDER RP-HPLC CONDITIONS
S. A. Dzhabieva, S. V. Kurbatova, E. A. Kolosova
Samara National Research University, Samara, Russia
Keywords: бензотриазол, высокоэффективная жидкостная хроматография, индексы связанности, факторы удерживания, benzotriazole, high-performance liquid chromatography, connectivity indices, retention factors
Abstract
Sixth order connectivity indices are calculated for 29 benzotriazole derivatives. Correlations between the connectivity indices, physicochemical characteristics, and retention factors of the mentioned compounds are obtained for reversed-phase high-performance liquid chromatography conditions. Based on the correlations obtained, a predictive calculation of the retention factors of some benzotriazole derivatives is performed.
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