STRUCTURAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF A SILVER(I) COMPLEX OF ARGININE
S. Ahmad1, A. Yousaf1, M.N. Tahir2, A.A. Isab3, M. Monimul-Mehboob3, W. Linert4, M. Saleem5
1University of Engineering and Technology, Lahore 54890, Pakistan
2University of Sargodha, Sargodha, Pakistan
3King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia
4Vienna University of Technology, A-1060 Vienna, Austria
5Jubail University College, P. O. Box 10074, Jubail Industrial City 31961, Saudi Arabia
Keywords: synthesis, silver nitrate, amino acids, arginine, crystal structure
Abstract
A silver(I) complex of arginine (arg), [Ag(arg)]NO3×0.5H2O (1) was prepared and characterized by elemental analysis, IR and NMR spectroscopy, and X-ray crystallography. The IR and NMR spectroscopic data confirmed the coordination of the ligand to silver(I). The structure of 1 shows that it is polymeric with each silver atom bound to the carboxyl O atom of one arginine ligand and to the amino N atom of another adopting a linear coordination environment. The two coordinate N-Ag-O units are repeated to form infinite chains. The molecular structure is stabilized by N-H…O and C-H…O hydrogen bonds. Antimicrobial activities of the complex were evaluated by minimum inhibitory concentration against gram-negative bacteria ( E. coli , P. aeruginosa ), molds ( A. niger, P. citrinum ) and yeasts ( C. albicans, S. cerevisiae ).
|
