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The journal "Ateroskleroz"

2015 year, number 2

MECHANISMS OF ORGANIZATION DEGENERATIVE AORTIC VALVE STENOSIS IN ELDERLY PATIENTS WITH ARTERIAL HYPERTENSION

G.N. Vereshchagina, E.A. Chibisova, I.M. Mitrofanov, O.V. Lisichenko
Novosibirsk State Medical University, 630091, Novosibirsk, Krasnyi av., 52
Keywords: degenerative aortic valve stenosis, nonobstructive aortal calcification, arterial hypertension, hypofunction of thyroid gland, parathyroid glands, hyperuricemia

Abstract

The aim of the present work was to investigate hemodynamic, hormonal, metabolic determinants and their correlations in patients with aortic valve stenosis and nonobstructive aortal calcification. 212 patients elder than 60 years with arterial hypertension were under observation. Were shown that hyperuricemia and hypothyroids to be significantly frequent detected in patients with nonobstructive aortic calcification if compared with patients with aortic valve stenosis. Possible mechanisms of organization degenerative aortic valve stenosis including parathyroid glands hyperfunction and genetic determinants were discussed.