STRUCTURE AND BIOLOGICAL EVALUATION OF (E)–5–BROMO–2–METHOXY–4–((PHENYLIMINO)METHYL)PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS
W. Zhou, J. Ma, R.-J. Yuan, X. Han, H.-G. Liu, H.-L. Zhu
Shandong University of Technology, ZiBo 255049, P. R. China
Keywords: vanillin derivatives, Schiff base, crystal structure, antibacterial activity
Abstract
Three (E)-5-bromo-2-methoxy-4-((phenylimino)methyl)phenol derivatives (1-3) are synthesized and characterized by elemental analysis and single-crystal X-ray diffraction. The antibacterial activities of compounds 1-3 against Escherichia coli , Pseudomonas aeruginosa , Bacillus subtilis , and Staphylococcus aureus are evaluated by the MTT method.
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