DETECTION OF A SMALL ADMIXTURE OF ACETONE IN THE EXHALED AIR FOR NONINVASIVE DIAGNOSIS OF TYPE I DIABETES
S. N. Atutov1, N. A. Danilina1, S. L. Mikerin1, A. I. Plekhanov1, M. M. Andrushkevich2, E. N. Surkov3
1Institute of Automation and Electrometry, Siberian Branch, Russian Academy of Sciences, pr. Akademika Koptyuga 1, Novosibirsk, 630090 Russia
2Presidium of the Siberian Branch of the Russian Academy of Medical Sciences, ul. Timakova 2, Novosibirsk 630117 Russia
3Research Institute of Physiology and Fundamental Medicine, Siberian Branch, Russian Academy of Medical Sciences, ul. Timakova 4, Novosibirsk, 630117 Russia
Keywords: gas analyzer, glow discharge, spectroscopy, noninvasive medical diagnostics
Abstract
A method for measuring the concentration of a biomarker (acetone in human’s breath), which is based on the use of glow-discharge emission spectroscopy in air is proposed for the purpose of noninvasive glucose monitoring in diabetes patients’ blood. The experimental setup and measurement techniques are described, and preliminary results of clinical trials of the developed system under ambulatory conditions are presented.
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