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The journal "Ateroskleroz"

2013 year, number 3-4

HYPERURICEMIA AND DEGENERATIVE PATHOLOGY OF AORTIC VALVE IN ELDERLY PATIENTS

G.N. Vereshchagina1, E.A. Chibisova2, I.M. Mitrofanov2, A.V. Shabalin2
1SEI HPE В«Novosibirsk State Medical University Minhealthsocdevelopment», Novosibirsk
2SE В«Scientific Center of clinical and experimental medicine SB RAMS», Novosibirsk
Keywords: arterial hypertension, nonobstructive aortal calcification, degenerative aortic valve stenosis, hyperuricemia, function of thyroid gland

Abstract

The purpose was to investigate a frequency of hyperuricemia and its relations with risk factors of degenerative pathology at patients who are elder than 60 years. Methods and result. We examined 212 patients with arterial hypertension and degenerative pathology of aortic valve, of which 76 with nonobstructive aortal calcification and 136 patients with aortic valve stenosis. In blood glucose level, lipids, uric acid, TTH and free T4 were defined. A frequency of hyperuricemia was 30.7 %, overt hypothyroidism 11,3 %, high normal TTH level 11.8 %. In women a combination of hyperuricemia and overt hypothyroidism was 39.3 %, in men it was 8.1 %. A negative correlation was found between glucose level and hyperuricemia.