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The journal "Ateroskleroz"

2013 year, number 3-4

ASSOCIATIONS OF RED CELL DISTRIBUTION WIDTH WITH CLINICAL AND LABORATORY CHARACTERISTICS OF ACUTE MYOCARDIAL INFARCTION

I.A. Urvantseva1, K.Yu. Nikolaev2,3, L.V. Salamatina1, A.A. Seitov1, E.V. Milovanova1, A.A. Nikolaeva2
1Regional Cardiologic Health Centre “Diagnostic and Cardiovascular Surgery Center, 628400, Surgut, Gubkin str., 1
2Institute of internal and preventive medicine SB RAMS, 630089, 175/1 B.Bogatkov St., Novosibirsk
3Novosibirsk State University, 630090, Novosibirsk-90, 2 Pirogov Str
Keywords: myocardial infarction, red cell distribution width, complications

Abstract

Red cell distribution width (RDW), a measure of circulating erythrocyte size heterogeneity, is a new predictor of myocardial infarction (MI) prognosis. The aim of this study is to evaluate the associations of RDW with clinical and laboratory parameters and gender characteristics of patients with acute myocardial infarction. A total of 250 patients (208 male and 42 female) with an ST elevation acute MI were examined. The RDW level was measured with an automated complete blood count. It did not differ in levels of RDW between male and female with MI. Series of associations were detected between RDW and carotid atherosclerosis ( r = +0.156, p = 0.013), chronic anemia ( r = +0.155, p = 0.014), with the presence of cancer ( r = +0.178, p = 0.005), pleural effusion ( r = +0.153, p = 0.015), thrombosis of the left ventricle ( r = +0.133, p = 0.036), acute encephalopathy ( r = +0.178, p = 0.005), leukocytes ( r = +0.132, p = 0.037), platelet ( r = +0.195, p = 0.002), and sodium ( r = –0.232, p = 0.006). The most significant association of RDW with pleural effusion was detected according to the results of covariance analysis. This association has reflected influence of inflammation to complications acute MI.