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The journal "Ateroskleroz"

2012 year, number 2

THE IMPACT OF METABOLIC SYNDROME ON THE CLINICAL COURSE OF ACUTE MYOCARDIAL INFARCTION

T.A. Mal’kova, A.D. Kuimov, M.I. Voevoda
Keywords: myocardial infarction, metabolic syndrome
Pages: 21-26

Abstract

Myocardial infarction (MI) continues to be one of the most important problems of modern cardiology in Russia due to maintaining a sustainable morbidity and mortality. Of particular interest are the growth of the relationship of cardiovascular disease and myocardial infarction with the accumulation in the population of persons with obesity and other metabolic disorders. Now to have a clear view of the relationship of metabolic syndrome and cardiovascular disease. Mechanisms of metabolic syndrome, including insulin resistance, hyperinsulinemia, chronic inflammation, run and maintain a high level atherogenesis, endothelial dysfunction, provoke instability of coronary plaque, thrombus formation processes. This is a strong incentive to continue research in this area, which should help to find new ways of preventing MS to reduce the possible coronary risk, affect the outcome of treatment and to determine the characteristics of MI, developed on the background of MS.