PREVENTION AND TREATMENT OF THE COGNITIVE DISORDERS OF LATE AGE BY USE OF THE POLYUNSATURATED FATTY ACIDS: CURRENT STATE AND PERSPECTIVES
A.V. Sukhanov
Keywords: cognitive disorders of the old age, Alzheimer's disease, omega-3 unsaturated fatty acids, docosahexaenoic acid, eicosapentaenoic acid, preventive measures, treatment
Pages: 54-61
Abstract
The article discusses the possibility of using of polyunsaturated fatty acids for prevention and treatment of cognitive disorders in old age. Current state and prospects of using of the eicosapentaenoic acid and the docosahexaenoic acid for this purpose are analyzed. Considering a demographic trends in developed countries in recent decades, the growing proportion of the elderly and the accompanying increase of frequency of the neurodegenerative diseases, it seems appropriate the prophylactic administration of a polyunsaturated fatty acids. It is clear that the prevalence of atherosclerosis-related disease (coronary heart disease, myocardial infarction) and its risk factors (arterial hypertension, obesity, diabetes mellitus, hyperhomocysteinemia) vary in different populations and lower in Mediterranean regions due to nutrition peculiarities such as consumption of polyunsaturated fatty acids. In addition, it is shown that the risk factors for Alzheimer's disease and atherosclerosis-related diseases are similar.
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