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Chemistry for Sustainable Development

2008 year, number 2

Effect of Amino Acids, Magnesium Ions and Hydroxyapatite on the Formation of Oxalate Nephroliths

A. R. Izatulina, O. A. Golovanova, Y. O. Punin
Keywords: nephroliths, calcium oxalate monohydrate, urinary components, dispersion analysis
Pages: 163-167


Processes of crystallization of calcium oxalate monohydrate from aqueous solutions and the effect of amino acids on these processes were investigated. It is shown that amino acids inhibit the growth of crystals of the compounds under investigation; the inhibiting action of an amino acid depends on its structure and increases with an increase in its concentration. The inhibiting effect on the crystallization of calcium oxalate monohydrate is also produced by magnesium ions in the concentration corresponding to the physiological solution (urine). It is demonstrated that the presence of hydroxyapatite crystals in solution initiates the crystallization of calcium oxalate monohydrate.