Mechanoactivated Medicinal Preparation of Calcium Gluconate: X-Ray Diffraction, Microscopic, and X-Ray Electron Investigations
G. N. KONYGIN1, F. Z. GILMUTDINOV1, S. G. BYSTROV1, O. V. KARBAN1, G. A. DOROFEEV1, E. P. YELSUKOV1, A. A. SHAKOV1, N. S. STRELKOV2, E. P. TYUL'KIN2, V. V. POZDEEV2, S. B. SHISHKIN2, P. N. MAKSIMOV2, A. N. FILIPPOV2 and V. V. KOREPANOVA2
1Physical-Technical Institute, Ural Branch of the Russian Academy of Sciences,
Ul. Kirova 132, Izhevsk 426001 (Russia) E-mail: konygin@fnms.fti.udm.ru
2Izhevsk State Medical Academy, Ul. Kommunarov 281, Izhevsk 426034 (Russia)
Pages: 249-252
Abstract
Mechanoactivation method has been applied to an officinal medical preparation of calcium gluconate for obtaining its modified form. It was found by X-ray diffraction and microscopic investigation techniques that the mechanoactivated powder constitutes X-ray amorphous, nanodispersed product with particle size from 50 to 500 nm. X-ray electron spectral analysis revealed no basic changes in chemical composition of calcium gluconate upon mechanoactivation.
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