Potential of Mechanochemical Technology in Organic Synthesis and Synthesis of New Materials
ALEXANDER V. DUSHKIN
Institute of Solid State Chemistry and Mechanochemistry, Siberian Branch
of the Russian Academy of Sciences, Ul. Kutateladze 18, Novosibirsk 630128 (Russia), E-mail: dushkin@solid.nsk.su
Pages: 251-273
Abstract
Possible applications and advantages of mechanochemical technologies are formulated. They include one-stage chemical reactions between solids, preparation of solid disperse systems (aggregates) of chemically interacting solids, formation of solid solutions, formation of solid reagents possessing increased activity in subsequent chemical transformations, and chemical modification of natural polymers. Comparative tests of activator mills have been carried out, recommendations for their application depending on the type of product have been worked out, and methods for ranging some mechanochemical processes for "flow" vibratory centrifugal mills have been developed. An original, readily soluble pharmaceutical of acetylsalicylic acid and its production process have been developed. The advantages of mechanochemical technology include one-stage process (mechanical treatment of the powdered material), absence of solvents and technological operations using them, simplification and increased productivity of technological equipment compared to equipment typically used in liquid-phase processes, and reduced
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