Safety of the Use of Aerosol Form of Cephalosporin Antibiotics for Lungs (Experimental Study)
S. V. AN’KOV1,2, M. S. BORISOVA1, T. G. TOLSTIKOVA1,2, A. M. BAKLANOV2, S. V. VALIULIN2
1Vorozhtzov Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Science, Novosibirsk, Russia
2Voevodsky Institute of Chemical Kinetics and Combustion, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
Keywords: aerosol, cefazolin, cefuroxime, cefotaxime, histology, mice, lungs
Abstract
The safety of administering aerosolised cephalosporin antibiotics is evaluated, relying on the results of histological examination of lungs after inhalation for different time intervals. Long-term inhalation is detected to cause no toxic effect on the lungs.
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