Home – Home – Jornals – Chemistry for Sustainable Development 2023 number 3

Ferulic acid (FA) is a phenolic substance widespread in plants and exhibiting a wide range of potential therapeutic effects, such as antimicrobial and anti-inflammatory, and useful in the treatment of diabetes, lung and cardiovascular diseases. Methanol extracts from the fresh leaves of 40 species from the Lamiaceae family growing in the outdoor collections of the Botanical Garden of the Komarov Botanical Institute of the Russian Academy of Sciences (BIN RAS, Saint-Petersburg) and the experimental station "Otradnoye" BIN RAS (Leningrad region) have been investigated. Ferulic acid was detected in 18 species under investigation, related to the subfamilies Lamioideae Harley ( Betonica grandiflora Willd., Galeobdolon luteum Huds., Lamium album L., Sideritis taurica Steph. ex Willd., Stachys byzantine K. Koch) and Nepetoideae Kostel. ( Clinopodium vulgare L., Hyssopus officinalis L., Lavandula angustifolia Mill., Meechania urticifolia (Miq.) Makino, Melissa officinalis L., Mentha piperita L., Monarda didyma L., Nepeta bucharica Lipsky, Nepeta grandiflora M. Bieb., Origanum vulgare L., Prunella laciniata (L.) L., Salvia desertum L., Salvia officinalis L., Thymus serpillum L.). Ferulic acid was not detected in the representatives of Ajugoideae Kostel. и Scutellarioideae Caruel subfamilies. For 7 species, FA was detected for the first time. The content of FA in the representatives of Lamiaceae subfamily varied within a broad range from 0.01±0.00 mg/g ( Meechania urticifolia ) to 6.68±1.30 mg/g ( Melissa officinalis L.). The high ferulic acid content was established in the Nepetoideae subfamilty in the species Melissa officinalis (6.68±1.30 mg/g) and Origanum vulgare L. (6.07±1.90 mg/g).