Effect of Rhaponticum carthamoides and Vaccinium oxycoccus Meal Plant Extracts Composition on Performance in the Mouse Forced Swim Test
a:2:{s:4:"TEXT";s:64:"D. A. KHALIKOVA, S. V. AN’KOV, YU. V. MESHKOVA, T. G. TOLSTIKOVA";s:4:"TYPE";s:4:"text";}
Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
Keywords: extract, leuzea, cranberry meal, ecdisten, ursolic acid, forced swim test
Pages: 654-659
Abstract
The effect of leuzea (Rhaponticum carthamoides) and cranberry (Vaccinium oxycoccus) meal extracts composition at a dose of (70 + 500) mg/kg, as well as individual active substances (ecdisten and ursolic acid) in equivalent doses, on the biochemical parameters of physical endurance (lactate, glucose) in the forced swim test on CD-1 male mice is investigated. It has been established that the developed composition exhibits pharmacological effects similar to those of the individual active substances promoting a decrease in the concentration of glucose (in blood) and lactate (in blood and in muscles).
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