Effect of Rhaponticum carthamoides and Vaccinium oxycoccus Meal Plant Extracts Composition on Performance in the Mouse Forced Swim Test
D. A. KHALIKOVA, S. V. AN’KOV, YU. V. MESHKOVA, T. G. TOLSTIKOVA
Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
Keywords: extract, leuzea, cranberry meal, ecdisten, ursolic acid, forced swim test
Pages: 654-659
Abstract
The effect of leuzea (Rhaponticum carthamoides) and cranberry (Vaccinium oxycoccus) meal extracts composition at a dose of (70 + 500) mg/kg, as well as individual active substances (ecdisten and ursolic acid) in equivalent doses, on the biochemical parameters of physical endurance (lactate, glucose) in the forced swim test on CD-1 male mice is investigated. It has been established that the developed composition exhibits pharmacological effects similar to those of the individual active substances promoting a decrease in the concentration of glucose (in blood) and lactate (in blood and in muscles).
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