THE STATE OF NUTRITIONAL STATUS AND ITS IMPACT ON THE LEVEL OF COMORBIDITY IN PATIENTS ON HEMODIALYSIS
Inna Yevgen’evna KOROLEVA1, Yekaterina Eduardovna ABRAMOVA2, Nikita l’vovich TOV2, Yelena Anatol’evna MOVCHAN2, Yuliya Vladimirovna OVECHKINA2, Anastasiya Borisovna LOGINOVA2
1Novosibirsk State Regional Clinical Hospital
inna.koroleva.1986@inbox.ru
2Novosibirsk State Medical University of Minzdrav of Russia
eamed1974@mail.ru
Keywords: гемодиализ, нутритивный статус, коморбидность, сердечно-сосудистые заболевания, биоимпедансометрия, мультиспиральная компьютерная томография
Abstract
The aim of the study was to
investigate the nutritive status and identify risk factors for
cardiovascular disease in patients on hemodialysis. Material and
methods. 144 patients on program hemodialysis were examined. All
patients underwent general clinical and laboratory examination, lipid
profile was examined, body mass index was calculated, waist and hip
circumference was measured, ratio of waist circumference to the
circumference of hip was determined, abdominal integral multi-frequency
bioimpedansometry and multispiral computed tomography were performed.
Results. Gender features of distribution of abdominal adipose tissue and
dyslipidemia in patients on program hemodialysis were revealed. Women
have a predominant accumulation of visceral adipose tissue, while men
are characterized by a proportional distribution of subcutaneous and
visceral adipose tissue in the abdominal area. Women compared to men
have higher rates of atherogenic lipoprotein fractions, which level is
closely related to the volume of visceral adipose tissue. Among the
comorbidities in the examined patients, diseases of the cardiovascular
system predominate. The regression analysis revealed that the most
significant risk factor for the development of coronary artery disease
is an increase in low-density lipoproteins, for chronic heart failure -
an increase in waist circumference. Conclusions. The data obtained
indicate the need to monitor the nutritional status of patients on
hemodialysis to identify and correct risk factors for cardiovascular
disease.
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