NOVOSIBIRSK REGION PROGRAM OF THE LIVER TRANSPLANTATION IN CHILDREN
Ivan Anatolyevich PORSHENNIKOV1, Alexander Yurievich BYKOV2, Maria Aleksandrovna KOROBEYNIKOVA3, Ekaterina Gennadyevna YUSHINA3, Vladimir Nikolaevich PAVLIK3, Elena Evgenyevna SHCHEKINA3, Konstantin Yuryevich BELOBORODOV3, Kirill Andreevich GRYAZNOV3, Svetlana Viktorovna DANCHENKO3, Anna Baynazarovna NIKULINA1, Irina Gennadievna GRINBERG3, Elena Ivanovna STRELTSOVA1, Anatoly Vasilyevich YUDANOV1
1State Novosibirsk Regional Clinical Hospital, Novosibirsk State Medical University of Minzdrav of Russia
porshennikov@oblmed.nsk.ru
2Novosibirsk State Medical University of Minzdrav of Russia
bykov@oblmed.nsk.ru
3State Novosibirsk Regional Clinical Hospital
transp@oblmed.nsk.ru
Abstract
The aim of the study was to
analyze the early and late outcomes of pediatric liver transplantation
(LTx) program in the Novosibirsk region. Material and Methods. The
retrospective study included 24 patients aged 72 ± 74.8 months (from 4
to 212 months, median - 20 months) with a body weight of 21.7 ± 18.1 kg
(from 4.5 to 55 kg, median - 12.5 kg). Two (8.3 %) cadaveric whole liver
grafts, 19 (79.2 %) living donor liver grafts, and 3 (12.5 %) cadaveric
liver fragments (reduced-size or split-liver) were transplanted.
Results. The features of vascular and biliary reconstruction in
different types of LTx are discussed. The incidence of vascular and
biliary complications was 8.3 and 20.8%, respectively. The patients
stayed in the intensive care unit for 9 ± 5.1 days (from 4 to 22 days,
median 8 days) and total length of hospital stay was for 40 ± 25.4 days
(from 19 to 136 days, median 32 days). Two (8.3 %) recipients had early
graft dysfunction. Perioperative mortality (up to 90 days) was absent.
The overall 5-year patient and graft survival rates were 95 and 88 %,
respectively. Conclusion. The Novosibirsk region has a pediatric LTx
program with outcomes comparable to the data of the leading world and
Russian centers.
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