COMPARATIVE ANALYSIS OF MARKERS EFFICIENCY OF VISCERAL OBESITY DETECTION IN MEN WITH METABOLIC SYNDROME
Denis Andreevich DEEV, Boris Borisovich PINKHASOV, Vera Georgievna SELYATITSKAYA, Tatyana Remonovna MATSIEVSKAYA, Iraida Georgievna MOKHOVA
Federal Research Center for Fundamental and Translational Medicine
Keywords: мужчины, висцеральное ожирение, метаболический синдром, окружность талии, отношение окружности талии к окружности бедер, толщина эпикардиального жира, men, visceral obesity, metabolic syndrome, waist circumference, waist to hip circumference ratio, epicardial fat thickness
Abstract
The purpose of the study
was to carry out comparative and quantitative assessment of surrogate
markers of visceral obesity and their connection with the severity of
clinical, biochemical and hormonal disorders in men with the metabolic
syndrome and obesity. Material and methods. 136 men, aged from 23 to 68
years, who were patients of therapeutic clinic were observed. Clinical,
anthropometric, biochemical and hormonal screening was taken.
Transthoracic echocardiography was performed in all patients. Criteria
of international experts’ consensus in the fields of cardiology and
endocrinology (2009) were used to identify metabolic syndrome. Results
and discussion. It was shown that among the all surrogate markers of
visceral obesity (waist circumference; waist circumference measured in
the lying position; waist circumference measured without the thickness
of the subcutaneous tissue; the ratio of waist circumference to the
circumference of the hips; sagittal abdominal diameter; thickness of
epicardial adipose tissue) the largest number of statistically
significant correlations with the clinical-biochemical, hormonal and
adipokine characteristics of men was found for the waist circumference,
measured in the lying position, and the waist circumference, measured
without the thickness of the subcutaneous tissue. Intermediate position
among the estimated markers was taken by a waist circumference measured
in a standing position. Fewer number of correlation connections were
revealed for thickness of the epicardial fat, sagittal abdominal
diameter and the ratio of waist circumference to the circumference of
the hips. Conclusion. The received results demonstrate objectivity of
the selection of the surrogate markers of the severity of visceral
obesity reviewed in the study, among which the waist circumference
measured in the lying position had the greatest efficiency.
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