INFLUENCE OF THE SPHEROPALATINE BLOCKADE ON THE CHANGE IN OXIDATION-REDUCTION POTENTIAL IN THE SURGICAL TREATMENT OF CONGENITAL CATARACT
Irina Gennadevna OLESHCHENKO1, Dmitriy Vladislavovich ZABOLOTSKIY2, Tatyana Nikolaevna YUREVA1,3, Marina Aleksandrovna GASPARYAN1, Yuliya Vladimirovna KURSAKOVA1
1Irkutsk Branch of Federal State Institution В«Eye Microsurgery» n.a. S. Fyodorov of Minzdrav of Russia
2St. Petersburg State Pediatric Medical University of Minzdrav of Russia
3Irkustk State Medical Academy of Postgraduate Education - Affiliated Branch of Russian State Medical Academy of Continuous Postgraduate Education of Minzdrav of Russia
Keywords: окислительно-восстановительный коэффициент, крылонебная блокада, вариабельность сердечного ритма, redox coefficient, spheropalatine blockade, heart rate variability
Abstract
Purpose of the study was to evaluate the influence of the spheropalatine blockade on the state of redox potential in the surgical treatment of congenital cataract in children. Materials and methods. A prospective, nonrandomized study included 52 patients who underwent planned surgery. The first group ( n = 26) included patients underwent anesthesia based on sevorane in combination with spheropalatine blockade as a regional component; a distinctive feature of 2nd group ( n = 28) was the implementation of a retrobulbar blockade as a regional component. The integral index in the form of the redox coefficient (FORD / FORT) before and after operation was estimated. The characteristic of heart rate variability in the frequency domain with the analysis of low frequency / high frequency parameters and the stress index of autonomic system was studied. Results and discussion. The obtained results convincingly show that the use of the spheropalatine blockade is accompanied by adequate antinociceptive protection of the body at the stage of the operative intervention and in the early postoperative period. The positive effect of prolonged regional analgesia is due to blockade not only of nociceptive pathways, but also of sympathetic innervation due to the effect on the periarterial sympathetic plexus of the internal carotid artery. The antioxidative and antinociceptive efficacy of the spheropalatine blockade is consistent with the positive dynamics of clinical indices. Thus, spheropalatine blockade in the surgery of congenital cataract in children is not only a method of postoperative analgesia, but also a therapeutic factor that has a significant positive effect on the outcome of surgical treatment in general.
|
