Reactions of 3,4-Dimethoxyphenylethylaminomethylidene Derivatives Tri- and Tetramethylene-4-Quinazolones and Formaldehyde
SH. N. ZHURAKULOV, M. G. LEVKOVICH, V. I. VINOGRADOVA
Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan
Keywords: deoxyvasicinone, mackinazolinone, 3-(3,4-dimethoxyphenylethyl)aminomethylidene-1,2,3,9-tetrahydropyrrolo[2,1-b]-quinazoline-9-one, 4-(3,4-dimethoxyphenylethyl)amino)-methylidene-1,2,3,4-tetrahydropyrido[2,1-b]-quinazoline-10-one
Pages: 265-269
Abstract
The reaction of 3-(3,4-dimethoxyphenylethyl)aminomethylidene-1,2,3,9-tetrahydropyrrolo[2,1-b]-quinazoline-9-one (3a), 4-(3,4-dimethoxyphenylethyl)amino)-methylidene-1,2,3,4-tetrahydropyrido[2,1-b]-quinazoline-10-one (3b) and formaldehyde in acid medium was studied. Instead of the expected Mannich products, bis-derivatives that are deoxyvasicinone and homoveratrylamine were obtained from 3а, and mackinazolinone - from 3b. The structure of the synthesized compounds was confirmed by data from IR, NMR and mass spectroscopy.
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