THE USE OF INTRAVENOUS FORMS OF BETA-BLOCKERS IN ACUTE CORONARY SYNDROME
I.D. Astrakhantseva1, I.A. Urvantseva1, K.Yu. Nikolaev2
1State-Financed Organization Khanty-Mansi Autonomous Region - Ugra District Cardiodispensary В«Centre of Diagnosis and Cardiovascular Surgery», 628403, Surgut, Lenin av., 69/1
2Institute of Internal and Preventive Medicine, 630089, Novosibirsk, Boris Bogatkov str., 175/1
Keywords: acute myocardial infarction, intravenous beta-blockers, metoprolol
Abstract
Beta- blockers are actively used in the treatment of patients with chronic and acute ischemic heart disease. Throughout the study period of effects of beta-blockers to limit myocardial necrosis at acute myocardial infarction (AMI) clinical researches were performed under pharmacological reperfusion of the coronary arteries; herewith the data about the clinical efficacy of beta-blockers of the patients with invasive strategy treatment of AMI are limited in international literature. The purpose of this review is to analyze the world literature on the use of injection forms of beta-blockers in acute coronary syndrome. Based on the analysis, it was concluded that the intravenous administration of metoprolol in the acute period of myocardial infarction clearly leads to the restriction of the necrosis zone, reduces the risk of repeated myocardial infarction and reduces the incidence of ventricular fibrillation.
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