MYOCARDIAL INFARCTION, STROKE: GENDER DIFFERENCES, DEVELOPMENTAL RISK AND PERSONAL ANXIETY AMONG THE POPULATION IN RUSSIA/SIBERIA (WHO PROGRAM “MONICA-PSYCHOSOCIAL”)
V.V. Gafarov1,2, E.A. Gromova1,2, D.O. Panov1,2, I.V. Gagulin1,2, A.V. Gafarova1,2
1Institute of Internal and Preventive Medicine, 630089, Novosibirsk, Boris Bogatkov str., 175/1
2Collaborative Laboratory of Cardiovascular Diseases Epidemiology
Keywords: risk, differences, high level of anxiety, population, myocardial infarction, stroke
Abstract
Objective: Тo determine the effect of a high level of personal anxiety on the difference in the risk of myocardial infarction (HR) and stroke in men and women in an open population of 25-64 years in Novosibirsk. Material and methods: A random representative sample of the population aged 25-64 years of Novosibirsk in 1994 (men n = 657, women n = 870) was examined in the framework of the III screening of the WHO MONICA-psychosocial program. The program included: registration of socio - demographic data, identification of personal anxiety (LT). Over a 16-year period, new cases of myocardial infarction (MI) and stroke were in women 15 and 35 cases; In men 30 and 22 cases, respectively. The statistical analysis was carried out using the SPSS version 11.5 software package. The criterion χ2 was used, for the development risk assessment (HR) - Cox-regression model (Cox-regression). Reliability in all types of analysis was adopted at a significance level of p ≤ 0,05. Results: In an open population of 25-64 years, VUT was defined in 59.9 % of women and 50.9 % of men. In the Cox single-factor model, after 16 years, HRM in persons with VUT was higher among women than among men (HR = 4.19 and HR = 3.7, respectively), and stroke was higher in men than in women (HR = 4.43 and HR = 3.5, respectively). In the multifactorial model of Cox in 55-64-year-old people, the influence of VUT on HRM was preserved, which was higher in women than in men (HR = 5.95, HR = 3.56, respectively). The greatest HR stroke, in the presence of VUT, was in divorced (HR = 5,017) and widowed men (HR = 3,848), aged 55-64 years (HR = 5,8). Among women, such patterns were not revealed. Conclusion: The prevalence of VUT among the population is more than 50 % and higher in women than in men . The risk of MI development over a 16-year period was higher in women, and in stroke in men.
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