Numerical Simulation of Cerebrospinal Fluid Hydrodynamics in the Healing Process of Hydrocephalus Patients
S. Gholampou1, N. Fatouraee2, A. S. Seddighi3,4, A. Seddighi3,4
1Islamic Azad University, Tehran, Iran
2Amirkabir University of Technology, Tehran, Iran
3Shahid Beheshti, Tehran, Iran
4University of Medical Sciences, Tehran, Iran
Keywords: сильвиев канал, давление спинно-мозговой жидкости, взаимодействие жидкости и твердого тела, число Рейнольдса, шунтирование, aqueduct of sylvius, CSF pressure, fluid-solid interactions, Reynolds number, shunting
Abstract
Three-dimensional computational models of the cerebrospinal fluid (CSF) flow and brain tissue are presented for evaluation of their hydrodynamic conditions before and after shunting for seven patients with non-communicating hydrocephalus. One healthy subject is also modeled to compare deviated patients data to normal conditions. The fluid-solid interaction simulation shows the CSF mean pressure and pressure amplitude (the superior index for evaluation of non-communicating hydrocephalus) in patients at a greater point than those in the healthy subject by 5.3 and 2 times, respectively.
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