STRUCTURE OF NEW DERIVATIVES OF PERHYDROPYRIMIDINE-2-ONES AND INTERMOLECULAR INTERACTIONS IN THEIR CRYSTALS
E. V. Mironova, D. B. Krivolapov, I. A. Litvinov, L. V. Mustakimova, V. A. Mamedov
Arbuzov Institute of Organic and Physical Chemistry, Russian Academy of Sciences, Kazan, Russia
Keywords: пергидропиримидин-2-оны, кристаллическая и молекулярная структура, рентгеноструктурный анализ, perhydropyrimidine-2-ones, crystal and molecular structure, single crystal X-ray diffraction
Abstract
Six new derivatives of perhydropyrimidine-2-ones obtained in a three-component system of urea, aromatic aldehydes, and dichloromethylacetylbenzoylmethanes are studied by single crystal X-ray diffraction. Molecules of the compounds studied have three chiral centers, but out of four possible diastereomeric pairs for each of compounds, the crystals of only one diastereomer are obtained, moreover, four of them crystallize as true racemates, two as racemic conglomerates. Crystals of five compounds are solvates with molecules of different nature (water, acetonitrile, dimethylformamide, dimethylsulfoxide). Crystals of the compounds studied are stabilized by both classical hydrogen bonds of N-H⋯O and O-H⋯O types and interactions of the С-H⋯O type.
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