Preparation and Study Microcapsules from Bioactive Hydroxyapatite
E. A. ZELICHENKO, V. V. GUZEEV, T. I. GUZEEVA, O. A. GUROVA, L. G. STEPANOVA
Seversk Technological Institute, Seversk, Tomsk Region, Russia
Keywords: гидроксиапатит биоактивный, микрогранулы, микрокапсулы, костная ткань, регенерация, биосовместимость, bioactive hydroxyapatite, microgranules, microcapsules, bone tissue, biocompatibility
Abstract
A synthesis technique of microgranules and microcapsules from bioactive hydroxyapatite was developed. Their structural and phase composition was investigated, electron microscopic analysis of the bioresorbable material was carried out. Biological and preclinical trials showed that when filling the bone defect with hydroxyapatite microgranules in animals a full-fledged bone tissue was formed.
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