Features and clinical significance of inflammatory markers in patients with metabolic syndrome with and without coronary heart disease
A.A. Efremushkina1, D.M. Rudakova2, E.N. Vorobyova1
1Altai State Medical University, 656049, Barnaul, Lenin av., 40
2KGBUZ Altai Regional Clinical Hospital, 656024, Barnaul, Lyapidevskiy str., 1
Keywords: апелин, метаболический синдром, ишемическая болезнь сердца, маркеры воспаления, аpelin, metabolic syndrome, coronary heart disease, inflammation markers
Abstract
Aim. To study endothelial function in patients with metabolic syndrome in thepresence or absence of coronary artery disease. Material and methods. Research included 82 male patients with existence of a metabolic syndrome aged from 39 to 72 years. Patients were divided into 2 groups after verification of the diagnosis. Group 1 ( n = 40) patients without symptoms of coronary atherosclerosis made, group 2 ( n = 42) - patients with existence of a coronary atherosclerosis. Results. At patients with a metabolic syndrome and existence of an ischemic heart disease it is reliable above such markers of an inflammation bsCRP, IL-6, TFN-α, selectin and reliable there is lower than a level of cardioprotective protein of an apelin. Conclusion. Definition of early predictors of coronary heart disease can significantly influence the individual program of treatment of the patient further.
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