CLINICAL STUDIES OF MONOCLONAL ANTIBODIES AGAINST THE PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9
K.S. Astrakova, Yu.I. Ragino, E.V. Shakhtshneider, M.I. Voevoda
Institute of Internal and Preventive Medicine, 630089, Novosibirsk, Boris Bogatkov str., 175/1
Keywords: proprotein convertase subtilisin/kexin type 9, PCSK9, hypercholesterolemia, Familial Hypercholesterolemia, Monoclonal antibodies
Abstract
The review presents the current data of scientific literature about different phases of clinical trials of monoclonal antibodies against the proprotein convertase subtilisin/kexin type 9 (PCSK9). The results of completed clinical trials and the review of clinical studies that will be complete in the 2015-2018’s are presented.
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