ASSOCIATION OF BLOOD RESISTIN LEVELS AND THE MAIN COMPONENTS OF METABOLIC SYNDROME AMONG OILMEN IN WESTERN SIBERIA
I.I. Logvinenko, Ya.S. Koleda, Yu.I. Ragino, E.V. Kashtanova, Ya.V. Polonskaya
Institute of Internal and Preventive Medicine, 630089, Novosibirsk, Boris Bogatkov str., 175/1
Keywords: components of metabolic syndrome, resistin, abdominal obesity, hypertension, risk of development of cardiovascular diseases, workers of the oil industry
Abstract
The purpose of this research is to examine resistin levels in blood serum and frequency of the main components of metabolic syndrome among oilmen working in shifts in Western Siberia. The research design is cross-sectional study. The research object is 125 men working in the oil industry in Western Siberia at the age of 30-45 (mean age is 35.3±3.5). Examination methods are anthropometry, measurement of blood pressure, electrocardiogram and determination of total cholesterol, glucose and resistin in blood plasma. Statistical data processing was performed using the Statistica 8.0 software package. 73.6 % of the examined men had certain components of metabolic syndrome: abdominal obesity (32.8 %), hypertension (23.2 %), hypercholesterolemia (59.2 %). The combination of these features was observed in 52.17 % of cases. 43.2 % of oilmen had overweight, 36.0 % - high normal blood pressure. Resistin concentrations in plasma fluctuated within 2.75-25.52 ng/ml (mean value is 4.85±2.06 ng/ml). Evaluating an extent of interrelation on the Cheddock scale, statistically significant p < 0.05 dependence of resistin concentration in plasma and blood pressure level was revealed: in case of systolic blood pressure the dependence was reverse and noticeable; it is direct and high in the event of diastolic blood pressure. Association with BMI was direct and noticeable.
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