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The journal "Ateroskleroz"

2015 year, number 1

ENDOTHELIUM-DEPENDENT VASCULAR REACTIVITY IN CORONARY ATHEROSCLEROSIS AND RISK FACTORS

A.A. Nikolaeva1, K.Yu. Nikolaev1, A.K. Ovsyannikova1, G.I. Lifchits2
1Reseaarch Institute of Internal and Preventive Medicine
2Institute of Chemical biology and Fundamental Medicine of SB RAS, 630090, Novosibirsk, Academik Lavrent’ev av., 8
Keywords: vascular reactivity, endothelium-dependent vasoactive substances, coronary atherosclerosis, risk factors

Abstract

In this review describes the peculiarities of endothelium-dependent vascular reactivity (EDVR) in patients with coronary atherosclerosis and its clinical manifestations. The mechanisms of the disorders EDVR due to the risk factors - arterial hypertension, smoking, family history of cardiovascular disease, high salt intake, etc are discussed in this paper.