THE STUDY OF ASSOCIATION BETWEEN LIPID FRACTIONS LEVELS AND ATTENTION
A.V. Sukhanov, D.V. Denisova, Yu.I. Ragino
Research Institute of Internal and Preventive Medicine of SB RAMS, 630089, Novosibirsk, Boris Bogatkov str., 175/1
Keywords: test Luria, cognitive function, serum lipids
Abstract
Background: The literature data about the association between attention disorders with lipid levels in young and middle age at the present time remains controversial. Objective: To examine the association of different levels of lipid fractions with level of attention at the each five-year period in both sexes aged 25-45 selected when performing a one-time survey of a random sample of Novosibirsk. Methods: The study involved 536 people aged 25 to 45 years - Novosibirsk residents of both sexes. The concentration of serum lipid levels were measured by enzymatic method. The level of attention was determined using the letter cancellation test (standardized for screening purposes). Analysis of the material was carried out using the methods of descriptive statistics, correlation analysis and multiple linear regression in the statistical package «R» for Windows. Results: Levels of total cholesterol and LDL showed a weak negative correlation with the number of errors in the letter cancellation test. At the same time, a positive correlation was found between the total number crossed out symbols in the letter cancellation test and total cholesterol and LDL levels. Conclusion: Association of lipid profile and the assessment of cognitive functions fails to recognize at a young age. Analysis of the associations in the future may be of great interest for the detailed development of the theory of memory.
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