ASSOCIATION OF CENTRAL AORTIC PRESSURE WITH COMPONENTS OF METABOLIC SYNDROME
E.E. Tsvetkova, A.A. Kuznetsov, A.V. Sukhanov, Yu.I. Ragino, M.V. Ivanova, S.N. Duma, V.V. Gafarov, M.I. Voevoda
Research Institute of Internal and Preventive Medicine of SB RAMS, 630089, Novosibirsk, Boris Bogatkov str., 175/1
Keywords: Central aortic pressure, components of the metabolic syndrome, hypertriglyceridemia
Abstract
Central aortic pressure (CAP) is regarded as a perspective indicator of the cardiovascular risk. It is interesting to study the association between the CAP and the components of the metabolic syndrome. We studied 69 individuals (46 women and 23 men) aged 56-78 years: 34 - research participants of the population sampling of Novosibirsk and 35 - outpatients. The components of the metabolic syndrome was determined according to the criteria of RSC 2009. Central aortic pressure was determined on a SphygmoCor (AtCor Medical, Australia). Omron HEM9000AI device (Omron, Japan) was used to calibrate the instrument. Data was analyzed in the GLM. Results are presented as mean value with a measure of the variation as an average error. Multivariate analysis with the simultaneous inclusion in the model age, sex, abdominal obesity, hypertriglyceridemia, hypo-alpha-cholesterolemia, hyper-beta-cholesterolemia, fasting hyperglycemia have revealed that only hypertriglyceridemia was a significant independent determinant of systolic and diastolic CAP ( p = 0,014 and p = 0,008, respectively) from all of analyzed components. The results of the study indicate that the central aortic pressure, regardless of age and sex was associated with only one component of the metabolic syndrome - hypertriglyceridemia.
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