CLINICAL AND PROGNOSTIC IMPORTANCE OF ASSESSMENT OF INTERLEUKIN-12 BLOOD CONCENTRATION IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS AFTER CAROTID ENDARTERECTOMY
A.V. FROLOV1,2, O.L. BARBARASH1,2
1Scientific-Research Institute for Complex Studying of Cardiovascular Diseases of SB RAMS, 650022, Kemerovo, Sosnovyi bulvar, 6
2Kemerovo State Medical Academy, 650029, Kemerovo, Voroshylov str., 22a
Keywords: интерлейкин-12, мультифокальный атеросклероз, каротидная эндартерэктомия, prognosis, interleukin-12, multifocal atherosclerosis, carotid endarterectomy
Abstract
54 patients, who were in the surgical department for subsequent carotid endarterectomy, were analyzed. Depending on long-term one-year prognosis all patients have been divided into two groups: with unfavorable (34 individuals - 62.9 %) and favorable (20 individuals - 37.1 %) prognosis. Interleukin-12 in serum was investigated in all patients in preoperative period. It was proved that patients who had such cardiovascular events as stroke, transient ischemic attack, myocardial infarction, death, and courses deterioration of multifocal atherosclerosis in any arterial region, increase or clinical presentations onset of ischemia in any organ during the first year after surgical procedure had significantly higher level of interleukin-12 in serum.
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