CRYSTAL STRUCTURE OF TWO HYDRATE phases of ciprofloxacindi-um TETRACHLORIDOCOBALTATE(II)
A. D. Vasiliev1,2, N. N. Golovnev3
1L. V. Kirensky Institute of Physics, Siberian Division, Russian Academy of Sciences, Krasnoyarsk
2Siberian Federal University
3Siberian Federal University, Krasnoyarsk
ngolovnev@sfu-kras.ru
Keywords: ciprofloxacindi-um tetrachloridocobaltate(II), crystal structure, hydrogen bonds, π–π interaction
Subsection: SUPRAMOLECULAR AND NANODIMENSIONAL SYSTEMS
Abstract
New (C17H20FN3O3)2[CoCl4]2×3H2O (I) and C17H20FN3O3[CoCl4]×H2O (II) compounds, where C17H18FN3O3 is ciprofloxacin (CfH), are synthesized and their crystal structures are determined. Crystallographic data for I: a = 18.441(5) Å, b = 9.030(3) Å, c = 27.551(8) Å, V = 4588(4) Å3, space group Pca21, Z = 4; for II: a = 9.305(3) Å, b = 9.885(3) Å, c = 12.999(4) Å, α = 82.782(4)°, β = 72.954(4)°, γ = 89.736(4)°, V = 1133(1) Å3, P–1 space group, Z = 2. Both structures contain CfH32+ ion pairs bonded by the π–π interaction. Additionally, in the crystal of I there is a stacking interaction between the π clouds of aromatic rings and hydrogen atoms of the cyclopropyl group linking the pairs of molecules with each other. The structure of the centrosymmetric crystal of triclinic phase II is also formed from CfH32+ ion pairs bonded by the π–π interaction, which, in this case, are not independent because they are related by the symmetry center. Hydrogen bonds form a branched three-dimensional network linking the CfH32+ and CoCl42– ions and water molecules.
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