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Chemistry for Sustainable Development

2011 year, number 6

Interaction of Glycyrrhizic Acid with the Products of Cholesterol Oxidation: a New View of the Problem of Atherosclerosis

O. YU. GLUSHCHENKO,В В N. E. POLYAKOV and T. V. LESHINAВ В 
Institute of Chemical Kinetics and Combustion, Siberian Branch of the Russian Academy of Sciences,
Ul. Institutskaya 3, Novosibirsk 630090 (Russia)
olga.gluschenko@gmail.com
Keywords: cholesterol oxidation, ozone, glycyrrhizic acid, atherosclerosis, cholesterol complex
Pages: 605–609

Abstract

The ability of glycyrrhizic acid to form complexes with the products of cholesterol oxidation was studied. The effect of complexing on the rate of cholesterol oxidation with ozone was studied. It was shown that the formation of complex with glycyrrhizic acid may become an efficient approach to govern the level of cholesterol inside and outside of cell membranes, and to extract the products of cholesterol oxidation.

UDC 542.61:547.913