Reactions of ОІ-Pinene Epoxide with Some Amines under the Action of Microwave Radiation
S. S. Laev, V. V. Fomenko, N. I. Komarova, D. V. Korchagina, N. F. Salakhutdinov
Keywords: ?-pinene epoxide, amines, amino alcohols, chromatography
Pages: 161-166
Abstract
Interaction of β-pinene epoxide with some amines (butylamine, diethylamine, piperidine, morpholine) under the action of the microwave radiation is investigated. It is established that opening of the epoxide cycle occurs in all the cases, and mainly a pair of isomeric amino alcohols (2-{amino-methyl}-6,6-dimethyl-bicyclo[3.1.1]heptane-2-ols) is formed. In all the experiments involving column chromatography, one of the isomers was isolated and characterized; for piperidine, both isomers were. characterized. In the experiment with butylamine, 1-para-menthene-7,8-diol was isolated from the reaction mass; in the case of diethylamine, an amino alcohol of menthane structure was isolated.
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