Betulin and Its Derivatives. Chemistry and Biological Activity
G. A. TOLSTIKOV1, O. B. FLEKHTER2, E. E. SHULTZ1, L. A. BALTINA2 and A. G. TOLSTIKOV3
1Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences,
Pr. Akademika Lavrentyeva 9, Novosibirsk 630090 (Russia), E-mail: gtolstik@nioch.nsc.ru
2Institute of Organic Chemistry, Ufa Scientific Centre, Russian Academy of Sciences, Pr. Oktyabrya 71, Ufa 450054 (Russia)
3Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences, Ul. Lenina 13, Perm' 614000 (Russia)
Pages: 1-29
Abstract
The data on natural sources of betulin and methods of its extraction are systematized in the review. Transformations of betulin and its available derivatives are considered. The data on the biological activity of betulin, its natural and synthetic analogs are presented. The promising character of the compounds based on betulin for creation of antiviral and antitumour agents.
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